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The Food and Drug Administration Office of Medical Products and Tobacco provides high-level coordination and leadership across the centers for drug, biologics, medical devices, and tobacco products. The office also oversees the agency's special medical programs.

Promotes integrity in research programs of the Public Health Service, both intramural and extramural, and responds to allegations of research misconduct.

The Director of National Intelligence (DNI) serves as the head of the Intelligence Community (IC), overseeing and directing the implementation of the National Intelligence Program and acting as the principal adviser to the President, the National Security Council, and the Homeland Security Council for intelligence matters related to the national security. Working together with the Principal Deputy DNI (PDDNI) and with the assistance of Mission Managers and four Deputy Directors, the Office of the DNI's goal is to effectively integrate foreign, military and domestic intelligence in defense of the homeland and of United States interests abroad.

The Office of the Federal Register is an agency of the United States government within the National Archives and Records Administration.

The Office of the Federal Register edits and publishes a number of important legal and rulemaking publications of the Federal Government, including the daily Federal Register, the annual Code of Federal Regulations, the United States Statutes-at-Large, the Public Papers of the President, and the U.S. Government Manual. Currently, its publications are all available online free of charge, including the eCFR, today's in effect edition of the Code of Federal Regulations.

It also administers the Electoral College.